We show that MAL accumulates at the ciliarybase of epithelial MDCK cells.
2
Yet, how this large complex passes through the size-dependent barrier at the ciliarybase remains enigmatic.
3
MAL, therefore, is crucial for the proper condensation of membranes at the ciliarybase, which is required for efficient primary cilium extension.
4
Although not a structural component of transition fibres, DYF-19 is required for the transit of assembled IFT particles through the ciliarybase.
5
These important ciliary events require transition fibers (TFs) that are positioned at the ciliarybase as symmetric nine-bladed propeller fibrous structures.
1
The last four genes encode structural components of the protein export apparatus in the flagellarbase, whereas FliK is soluble and secreted during flagellar assembly.